Study Links Ibuprofen to Male Infertility


Study Links Ibuprofen to Male Infertility

Some took 1,200 milligrams of ibuprofen daily, the maximum limit as directed, over a six-week period, while oOthers took a placebo.

This led, they said, to compensated hypogonadism, a condition linked to reproductive and other health problems normally found in elderly men.

Those in the ibuprofen group were given two doses of ibuprofen a day.

Epidemiological studies have shown that NSAID exposure was associated with reduced testosterone and congenital malformations; another study showed a drop in a testosterone metabolite among men who were taking ibuprofen regularly.

But a new study raises questions about the risks of frequent usage of ibuprofen by young men.

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Typically seen in older men and smokers, the condition describes when the testes produce an insufficient amount of testosterone. Bernard J├ęgou, co-author and director of the Institute of Research in Environmental and Occupational Health in France, and a team of French and Danish researchers, began by exploring the health effects of pregnant women taking any of the 3 most common OTC pain relievers: acetaminophen, aspirin, and ibuprofen. Before he stepped down in November 2016 he asked players about their use of over-the-counter painkillers and found that almost half of those who played in the past three World Cups took anti-inflammatory drugs, such as ibuprofen, every day.

The Consumer Healthcare Products Association is a trade group that represents manufacturers of over-the-counter medications and supplements.

Researchers published their findings in the Proceedings of the National Academy of Sciences, noting that consumption of ibuprofen resulted in "compensated hypogonadism", a condition in which men have normal levels of testosterone but higher levels of the luteinizing hormone, which stimulates the production of testosterone, The International Study for Sexual Medicine said. This is because the pituitary gland at the base of the brain had ramped up levels of another hormone that drives the production of extra testosterone.

The hormonal imbalance caused compensated hypogonadism, which is a condition linked to decreased male fertility, depression, and an increased risk of heart attack or stroke.

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