Russian Federation has waged a punishing aerial campaign against Syria's armed opposition since intervening in the civil war on the side of its ally, President Bashar Assad, in 2015. F-16 fighters of the Turkish Air Force are involved in the operation, inflicting strikes on the positions of PYD/YPG on the Syrian-Turkish border.
Mr Le Drian said global law was "being violated by the Damascus regime, by Iran and those who are attacking eastern Ghouta and Idlib", calling on all Iranian-backed militia, including Lebanon's Hezbollah, to leave Syria. "However, this desire [of the U.S.] will not be fulfilled". The plea comes amid reports heavy air strikes have killed dozens in the last major rebel stronghold near the capital Damascus.
The U.K. -based Syrian Observatory for Human Rights (SOHR) said that more than 70 people were killed in Tuesday's attacks. Sirens and wailing mixed with the relentless sound of airstrikes as residents of eastern Ghouta were unable to keep up with the onslaught.
"Now the rescue workers are searching for my second daughter but can't find her".
The bombing was one of the bloodiest in the eastern Ghouta region for over a month.
Two children and a woman were killed in the town of Saqba, the war monitor said.
"We're in emergency mode", Moumtzis said as he described the numbers of people who are hungry, displaced or in need of immediate medical treatment.
"Please break up all gatherings and clear the streets", blared an announcement from mosque minarets in Douma. Turkey began deploying forces in an observer role to rebel-held Idlib in October as part of the "de-escalation" agreement.
In apparent retaliation, rockets were fired on Damascus's Bab al-Touma neighbourhood, killing three civilians, the state news agency SANA reported.
The deal to ease violence in certain areas, brokered by Russian Federation with Turkey and Iran - as well as the rout of the Islamic State from most of its territory a year ago - may have given people the false impression that the Syrian war was winding down, Mr. Moumtzis said.
Chlorine is suspected of having been used on two occasions this month alone on Eastern Ghouta.More news: Anchorage police warn of 'heinous' child sex video circulating Facebook
The world's chemical watchdog voiced "grave concern" over the new reports. Damascus denied the White House's charges, and The Associated Press could not independently verify the reports of a chlorine gas attack.
Syrian state-run media said the Syrian army was responding to a shelling attack in Damascus by "armed groups" - an attack that they say killed five people - including two children - and injured 13 others.
An Israeli air strike hit the facility in May 2013.
Syria says the Israeli warplanes launched missiles while inside Lebanon.
Afrin, one of the few areas of Syria to know relative peace since 2011, has now been plunged into conflict in the last weeks.
Using an alternative acronym for IS, the coalition said it then "conducted strikes against attacking forces to repel the act of aggression against partners engaged in the Global Coalition's defeat-Daesh mission".
The U.S. and Russian Federation have been lashing out at each other for months over the issue of accountability for chemical attacks in Syria, which is a close ally of Moscow.
"We're here to ensure the lasting defeat of ISIS is maintained in this area", Lt. Gen. Paul E. Funk said during a visit to USA forces in Manbij. "If anything, these have been serious escalation areas". After seven years of conflict in Syria it appears many parties finally agree on something: they want the U.S. out of the country.
The organisation said the situation had reached "extreme" levels which "we haven't seen before".
"A member of the civilian defence died when he was saving people under the rubble in Arbeen".