Having missed out on selection for Argentina's most recent worldwide selection, behind Messi, Sergio Aguero and Gonzalo Higuain, Dybala has work to do if he is to force his way into his national side for this summer's World Cup. The Barcelona ace is recovering from a from a hamstring injury and was unused by Jorge Sampaoli in Argentina's comfortable 2-0 win over Italy in the ongoing global friendlies at Old Trafford.
Argentina coach Jorge Sampaoli said Messi trained "normally" on Monday and is available to play. "Argentina knows how to press, play, and when attacking, they are animals", he said. "The day before the match against Italy he said he wasn't fit to play and he didn't".
Messi, 30, led Argentina to the final of the 2014 World Cup, where they were beaten by Germany in Brazil.
"It is impossible to teach something to Messi".
"We are in a place where Leo is untouchable", added Sampaoli, before suggesting his team would be built around the advice he picked up from Messi.More news: Inside Donald Trump's affair with Playboy bunny weeks after Melania gave birth
Despite Dybala's superb talent, the Juventus striker may miss out on World Cup selection.
Even without Messi's injured Barca team-mate Sergio Busquets, Spain produced another impressive display of controlled football when they drew 1-1 away to Germany on Friday night. Alongside me in the national team he had to play more on the left, maybe he's not so used to that. On the right we can cut inside and we have the whole pitch in front of us.
But Spain and Argentina fans hoping for a glimpse of him will be disappointed at the match in Madrid tonight.
Lionel Messi has recovered from his adductor muscle problems and will play against Spain in a friendly on Tuesday.
"It's more hard for us to play there, I don't often go out to the left".