Salman, 31, was found not guilty of aiding and abetting material support to a foreign terror organization and of obstruction of justice.
Upon being notified that she was not guilty, Salman and a member of her legal team burst into tears.
Family members and spokespeople of Ms. Salman speak with members of the media outside a federal courthouse. She could be seen whispering "thank you" to her lawyers amid the favourable ruling. "More questions is better than no questions", said Salman spokeswoman Susan Clary. "She can go home now and try to pick up the pieces".
"I don't agree that she was a victim", she said, disagreeing with the defense's argument.
She didn't answer questions from the media, and hung onto the arm of her attorney as they walked to a waiting vehicle. Her husband, Omar Mateen, died during a shootout with police after he had entered the club and killed 49 people and injured 58.
Salman's attorneys argued she was not an accomplice in the case, but a victim.
Fellow defense attorney Charles Swift said he was impressed with the jury's attentiveness and the seriousness that they showed during the trial. They claimed she initially told investigators her husband acted without her knowledge but later said she knew he was watching Islamic State videos, had purchased an assault rifle, and examined three possible attack locations.
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They also told the court that Ms Salman and Mateen scouted out potential targets together - including Disney World's shopping and entertainment complex - and she knew he was buying ammunition for his AR-15 in preparation for an attack. She had faced a sentence of up to life in prison. Her family says that after spending a year in jail awaiting trial, her priority is to be reunited with her five-year-old son.
In one of multiple failed attempts at a mistrial, Salman's attorneys argued the government never told them that part of the statement had been proved false.
In a blow to the government's case, the Federal Bureau of Investigation itself found that receipts and cellphone signals showed the couple were nowhere near the Pulse on the day Salman said they were.
Since the defense launched its case Monday, Mateen's family and friends described her as a peaceful person and a good mother.
This June will mark two years since the horrific terrorist attack/hate crime.
"Nothing harmful would come out of her", a friend of Salman's who was identified only as Ms. Ahmed told jurors.
Salman was interviewed by authorities for 11 hours, and her IQ score is 84, which makes her "below average in intelligence", Frumkin said.
The revelation threatened to upend the case against Salman, but the judge denied the motion, saying it was not relevant.
A jury has cleared Noor Salman of all charges related to the 2016 shooting at the Pulse nightclub in Orlando.